Comparative evaluation of argyrophilic nucleolar organizer regions parameters in benign and malignant breast tumors

Aim. The aim of the paper was to evaluate AgNOR parameters for discrimination benign from malignant breast tumors via a new approach - total area/nuclear area (TAA/NA). Material and methods. Three groups, consisting control (n = 14), 18) 28) participants were included in study. staining technique performed both mean number TAA/NA ratio evaluated. Results. While differences between patient groups statistically significant (p < 0.001), it not group > 0.05). For TAA/NA, significant. Conclusion. We consider that evaluation rate, when compared with number, can be more sensitive useful tool distinguishing lesions.